Cell signalings are basic concepts for the understanding of energy homeostasis and control mechanism in living organisms. Especially, the relationships between the principles of signal transduction and the metabolic diseases such as diabetes and obesity will be focused to learn current trends and future subject of research in this area.
1) The components and principles of signaling for major receptors, switchs, 2nd messengers, protein kinases and scaffolds.
2) The machineries and mechanisms for the control of energy homeostasis in living orgamisms.
3) Current trends in the researches on the disorders in metabolism and diseases such as diabetes and obesity
4) The microbiome

Students may have understandings on basic cell biology.
-Students must prepare presentations for specific topics during the course of the later part of class

1) No examination

2) The rate of course attendance accounts for 40% of evaluation.
(If you are late for more than 5 minutes, you will be treated as absent - same rules for online live and online recorded course)
(11시 6분 부터는 결석 처리, 온라인 강의 및 온라인 녹화 강의도 마찬가지)

3) The other 60% will be based on your own presentations
and questions.
- Topics can be diseases associated with signaling alterations and microbiome etc.

9/3– Introduction (1)
9/5 – Introduction (2) – Fundamentals of signaling
9/10 – Subcellular localization of signaling molecules (recorded online)
9/12 – Ligands and Receptors (1) – GPCR (recorded online)
9/17 – No class (Korean Thanksgiving Day)
9/19 – No class (Korean Thanksgiving Day)
9/24 – Ligands and Receptors (2) - Receptor Tyr Kinases
9/26 – Role of posttranslational modifications
10/1 – Second messenger (recorded online)
10/3 - No class (National Foundation Day)
10/8 – Regulated protein degradation
10/10- Structural insight into functional selectivity of insulin receptor (Prof. Na-Oh Yunn, tentative) Summary note & 1 question at least
10/15 – Membranes, Lipids, and Enzymes that Modify Them
10/17 – Invited lecture (tentative)
10/22 – No class (Midterm Exam period)
10/24 – No class (Midterm Exam period)
10/29 – The Molecular Architecture and Evolution of Signaling Proteins
10/31 – Diversity of extracellular vesicles to understand their therapeutic potential (Dr. Kyungsu Park – A Recorded Lecture by an Overseas Researcher) (tentative)
11/5 – Microbiome & SCFAs
11/7- Scientific Writing (A Recorded Lecture)
11/12 – Bacterial outer membrane vesicle-mediated host-pathogen interaction and application (Dr. Kyungsu Park – A Recorded Lecture by an Overseas Researcher) (tentative)
11/14 – Bile acids & microbiome-metformin (A Recorded Lecture by an Overseas Researcher)
11/19 – Presentation/discussion
11/21 – Diet-gut microbiome interactions (A Recorded Lecture by an Overseas Researcher)
11/26 - Presentation/discussion
11/28 – Microbiome and metagenome (A Recorded Lecture by an Overseas Researcher)
12/3 – Presentation/discussion
12/5 – Presentation/discussion
12/10 - Presentation/discussion
12/12 – Applications of bacterial signal transduction pathways in synthetic biology – Dr. Minkyung Kang– Tentative

40% for the basics of cell signaling, 30% for the special topics and 30% for the presentation/discussion