3. 강의목표
Objective
Teaches basic experimental principles of biochemistry, biology & biophysics to conduct
interdisciplinary researches in biology, biological materials, and biotechnology fields
5. 성적평가
Evaluation
Midterm 30 %, Final 40 %, Homework 40 %, attendance 10%
8. 강의진도계획
Lecture 1: Experimental Strategy/Introduction
Part I. Proteins
Lecture 2: Issues, Research themes, Functions, and mechanism
(Case study: Experimental strategies in nucleic acid purifications/silica columns)
Lecture 3: Post-translational Modification
(Case study: Conus toxin)
Lecture 4: Amino acid reactivity (I) Cys/Lys
(Case study: Histone/Collagen)
Lecture 5: Amino acid reactivity (II) Phe/Tyr/Trp
Lectuure 6: Protein detection/Quatification/Spectroscopy
(Case study: Serotonin)
Lecture 7: Water reactivity/pH/pKa
(Case study: Enzyme active site)
Lecture 9: Hydrophobicity & Hydrophobic effect
(Case study: Cooking in a frying pan)
Lecture 9: Hydrophathy: The degree of hydrophobicity
(Case study: Signal peptide)
Lecture 10: Intermolecular forces and Intermolecular forces in water
(Case study: Mussel adhesive proteins)
Lecture 11: Light Spectroscopy : Absorbance & Fluorescence
(Case study: Reflectin)
Lecture 12: Amino acid chain flexibility
Lecture 13: Secondary structures (I)- alpha helix
(Case study: Antibacterial peptide)
Lecture 14: Secondary structure (II)-beta sheet
(Case study: Spider silk & silks)
Lecture 15: Secondary structure (III)- Polyproline type II
Lecture 16: Secondary structure (IV)- coiled-coil
(Case study: Hair & keratin)
Lecture 17: Liquid Crystals in biological materials
(Case study: Silk, collagen, cellulose, chitin)
Midterm
Part II. Structural Carbohydrates
Lecture 19: Sugar
(Case study: Blood types/Biosimilar)
Lecture 20: Sugar reactivity
(Case study: Diabate)
Lecture 21: Structural sugars
(Case study: Rayon & Nanocellulose)
Part III. Biomechanics
Lecture 22: Biomechanics & Elasticity & Load-bearing proteins
(Case study: Titin)
Lecture 23: Visco-elastic properties
(Case study: Titin)
Lecture 24: Optical Tweezer & Magnetic Tweezer
(Case study: Titin)
Lecture 25: Atomic force microscopy
(Case study: Titin)
Lecture 26: Surface forces apparatus
(Case study: Mussel adhesive proteins)
Part IV. Intrinsically disordered biomacromolecules
Lecture 27: Coacervate/LLPS/Condensate
(Case study: tau)
Part V. Techniques
Lecture 29: Biochemical analysis/purification
Final exam
11. 장애학생에 대한 학습지원 사항
- 수강 관련: 문자 통역(청각), 교과목 보조(발달), 노트필기(전 유형) 등
- 시험 관련: 시험시간 연장(필요시 전 유형), 시험지 확대 복사(시각) 등
- 기타 추가 요청사항 발생 시 장애학생지원센터(279-2434)로 요청