3. 강의목표
To explore the principles and applications of silicon-based electronic systems interfacing with biological environments, with a focus on biosensors, neural interfaces, lab-on-a-chip systems, and neuromorphic devices.
4. 강의선수/수강필수사항
Electrochemistry for Chemical Engineering (특강: 화공전기화학) 을 수강하면 듣기 수월합니다.
5. 성적평가
중간고사: Research Report (30%)
기말고사: Individual Presentation (40%)
출석 (30%)
7. 참고문헌 및 자료
Resources: Research papers and current trends in electrochemistry
Resources will be provided.
8. 강의진도계획
Week 1: Introduction & Course Overview
Course goals, structure, and grading
What is Si-bio interface engineering?
Overview of application areas: biosensing, neural interfaces, lab-on-a-chip, neuromorphic devices
Week 2: Basics of Electronic Materials
Semiconductor fundamentals (Si, PN junctions, doping)
Conductors, insulators, semiconductors
Introduction to the MOS structure
Week 3: Micro/Nano Fabrication Techniques
Introduction to cleanroom processes (photolithography, etching, deposition)
CMOS-compatible fabrication
Fabrication strategies for bio-integrated systems
Week 4: Fundamentals of Circuits and Sensors
Basic circuit elements (resistors, capacitors, op-amps)
Analog vs. digital signals
Common circuit designs for biosignal acquisition
Week 5: Understanding Bioelectrical Signals
Types of biological electrical signals (EEG, ECG, action potentials)
Physiological origin of electrical signals
Signal-to-noise challenges in bioelectronics
Week 6: Basics of Bioelectronic Interfaces
Electrochemical interfaces: electrode-cell interactions
Electric double layer, impedance, charge injection
Electrode materials: Au, Pt, PEDOT:PSS, etc.
Week 7: Biosensors I – Electrochemical Sensing
Potentiometric, amperometric, and conductometric sensors
Electrolyte–insulator–semiconductor (EIS) structures
Applications: DNA sensing, protein detection
Week 8: Biosensors II – FET-based Biosensors
ISFET, BioFET, Graphene FETs
Strategies to improve sensitivity and selectivity
Applications in bacterial and viral detection
Week 9: Neural Interfaces I – Recording Neuronal Signals
Basics of microelectrode arrays (MEAs)
Intracellular vs. extracellular signal acquisition
Engineering challenges in neuron-electrode interfaces
Week 10: Neural Interfaces II – Stimulation & Electroceuticals
Methods of electrical stimulation
Introduction to electroceuticals
Brain stimulation and neuromodulation case studies
Week 11: Lab-on-a-Chip & Organ-on-a-Chip Systems
Basics of microfluidics
Design and applications of biochips
Diagnostic chips and cell-culture systems
Week 12: Neuromorphic Devices & Artificial Synapses
Memristors, IGZO, phase-change memories
Comparison to biological synapses
Neuromorphic circuits and learning architectures
Week 13: Emerging Technologies in Bioelectronics
Flexible and wearable biosensors
Nanobiosensors (e.g., DNA origami, aptamer sensors)
Bioelectronics in artificial organ development
Week 14: Final Project Preparation
Project review and feedback
Design revisions and finalization
Week 15: Final Presentations & Discussion
Student presentations with Q&A
Discussion on future trends and real-world applications
Career paths in bioelectronics and interface engineering
9. 수업운영
- 대학원생 수강시 Grade로 신청 요망
- 기말고사의 경우, 15분 개인 발표 평가.
10. 학습법 소개 및 기타사항
최근 반도체-바이오 융합 연구에 대한 전반적인 내용을 다루며, 실험 참관을 통해 실제 연구로 어떻게 이어지는지까지 탐구하고자 함.
11. 장애학생에 대한 학습지원 사항
- 수강 관련: 문자 통역(청각), 교과목 보조(발달), 노트필기(전 유형) 등
- 시험 관련: 시험시간 연장(필요시 전 유형), 시험지 확대 복사(시각) 등
- 기타 추가 요청사항 발생 시 장애학생지원센터(279-2434)로 요청