Cell signalings are basic concepts for the understanding of energy homeostasis and control mechanism in living organisms. Especially, the relationships between the principles of signal transduction and the metabolic diseases such as diabetes and obesity will be focused to learn current trends and future subject of research in this area.
1) The components and principles of signaling for major receptors, switchs, 2nd messengers, protein kinases and scaffolds.
2) The machineries and mechanisms for the control of energy homeostasis in living orgamisms.
3) Current trends in the researches on the disorders in metabolism and diseases such as diabetes and obesity
4) The microbiome

Students may have understandings on basic cell biology.
-Students must prepare presentations for specific topics during the course of the later part of class

1) No examination

2) The rate of course attendance accounts for 40% of evaluation.
(If you are late for more than 5 minutes, you will be treated as absent - same rules for online live and online recorded course)
(11시 6분 부터는 결석 처리, 온라인 강의 및 온라인 녹화 강의도 마찬가지)

3) The other 60% will be based on your own presentations
and questions.
- Topics can be diseases associated with signaling alterations and microbiome etc.

9/6 – Introduction (1)
9/8 – Introduction (2) – Fundamentals of signaling
9/13 – Ligands and Receptors (1) – GPCR
9/15 – Role of posttranslational modifications
9/20 – Ligands and Receptors (2) - Receptor Tyr Kinases
9/22 – Subcellular localization of signaling molecules
9/27 – Second messenger
10/4 – Regulated protein degradation
10/6- Membranes, Lipids, and Enzymes that Modify Them
10/11 – The Molecular Architecture and Evolution of Signaling Proteins
10/13 – (Video 강의 – Scientific writing)
10/18 – Bacterial signaling I (Dr. Inyoung Jeong, POSTECH)
10/20 – Microbiome & SCFAs
10/25, 10/27 중간고사기간
11/1 – invited talk– 요약문 제출
11/3- Listening to the metabolic crosstalk between commensal and our bodies (recorded)
11/8 – invited talk– 요약문 제출
11/10 – Bile acids & microbiome-metformin (Recorded video)
11/15 – Presentation/discussion 1
11/17 – recorded lecture (diet-gut microbiome)
11/22 – Presentation/discussion 2
11/24 – Mucosa-associated microbiome(Recorded lecture)–
11/29 – invited talk– 요약문 제출
12/1 – recorded lecture
12/6 – Presentation/discussion 3
12/8 – invited talk– 요약문 제출
12/13 – Presentation/discussion 4
12/15 – invited talk– 요약문 제출

40% for the basics of cell signaling, 30% for the special topics and 30% for the presentation/discussion