Current research trend is on drastic shifts from identification of structures and functions of individual gene products to regulation and interaction of multiple proteins in living cells and furthermore intact organisms. Triggered by recent development of optical technologies, a number of unprecedented imaging methods are available now. In addition to imaging itself, a new powerful methodogy that takes advantage of existing methods recently emerges, optogentics. It would allow us to modulate a number of physiological features at the cellular level and also organism level, which can be potetially applicable to various approaches such as neuroscience. This lecture has been devised for students to understand principles of microscopes and learn about a variety of new molecular imaging methods, incluidng the recent application such as optogenetics.

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PPT materials, recent review and original research papers

1 week: Course introduction 2 week : Principles of optical imaging 3 week : Fluorescence microscopy I 4 week : Fluorescence microscopy II 5 week : Single molecule imaging 6 week : Molecular dynamics imaging I 7 week : Molecular dynamics imaging II 8 week : Mid exam 9 week : Medical imaging I 10 week : Medical imaging II 11 week : In vivo imaging I 12 week : In vivo imaging I 13 week : Beyond the limits- optogentics 1 14 week : Beyond the limits- optogentics 2 15 week : Medical Imaging 1 16 week : Final Exam

In person

Lectures 70%
Presentation & Discussion 30 %